Synthesis of Pyrrolo[1,2-a]pyrimidine Enantiomers via Domino Ring-Closure followed by Retro Diels-Alder Protocol

Synthesis of Pyrrolo[1,2-a]pyrimidine Enantiomers via Domino Ring-Closure followed by Retro Diels-Alder Protocol

From 2-aminonorbornene hydroxamic acids, a simple and efficient method for the preparation of pyrrolo[1,2-a]pyrimidine enantiomers is reported. The synthesis is based on domino ring-closure followed by microwave-induced retro Diels-Alder (RDA) protocols, where the chirality of the desired products i...

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Bibliographic Details
Main Authors: Beáta Fekete, Márta Palkó, Matti Haukka, Ferenc Fülöp
Format: Article
Language:English
Published: MDPI AG 2017-04-01
Series:Molecules
Subjects:
domino reactions
hydroxamic acid
microwave chemistry
N-heterocycles
retro Diels-Alder reaction
Online Access:http://www.mdpi.com/1420-3049/22/4/613

Internet

http://www.mdpi.com/1420-3049/22/4/613

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