The effect of glia-glia interactions on oligodendrocyte precursor cell biology during development and in demyelinating diseases

The effect of glia-glia interactions on oligodendrocyte precursor cell biology during development and in demyelinating diseases

Oligodendrocyte precursor cells (OPCs) originate in specific areas of the developing central nervous system (CNS). Once generated, they migrate towards their destinations where they differentiate into mature oligodendrocytes. In the adult, 5-8% of all cells in the CNS are OPCs, cells that retain the...

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Bibliographic Details
Main Authors: Diego eClemente, María Cristina eOrtega, Carolina eMelero-Jerez, Fernando eDe Castro
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-12-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Astrocytes
Microglia
Multiple Sclerosis
remyelination
Oligodendrogliogenesis
molecular cues
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2013.00268/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fncel.2013.00268/full

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