A matrix metalloproteinase-generated neoepitope of CRP can identify knee and multi-joint inflammation in osteoarthritis

A matrix metalloproteinase-generated neoepitope of CRP can identify knee and multi-joint inflammation in osteoarthritis

Abstract Objective To compare C-reactive protein (CRP) and matrix metalloproteinase-generated neoepitope of CRP (CRPM) as biomarkers of inflammation and radiographic severity in patients with knee osteoarthritis. Methods Participants with symptomatic osteoarthritis (n=25) of at least one knee underw...

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Bibliographic Details
Main Authors: Louie C. Alexander, Grant McHorse, Janet L. Huebner, Anne-Christine Bay-Jensen, Morten A. Karsdal, Virginia B. Kraus
Format: Article
Language:English
Published: BMC 2021-08-01
Series:Arthritis Research & Therapy
Subjects:
C-reactive protein (CRP)
Inflammation
Synovitis
Osteoarthritis
Biomarkers
Online Access:https://doi.org/10.1186/s13075-021-02610-y

Internet

https://doi.org/10.1186/s13075-021-02610-y

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