Sweet taste of heavy water

Ben Abu, Mason and colleagues use molecular dynamics, cell-based experiments, mouse models, and human subjects to determine that, unlike ordinary water, heavy water tastes sweet to humans, but not mice. Mechanistically, this effect is mediated by the human TAS1R/TAS1R3 sweet taste receptor.

Bibliographic Details
Main Authors: Natalie Ben Abu, Philip E. Mason, Hadar Klein, Nitzan Dubovski, Yaron Ben Shoshan-Galeczki, Einav Malach, Veronika Pražienková, Lenka Maletínská, Carmelo Tempra, Victor Cruces Chamorro, Josef Cvačka, Maik Behrens, Masha Y. Niv, Pavel Jungwirth
Format: Article
Language:English
Published: Nature Publishing Group 2021-04-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-021-01964-y