Protecting exons from deleterious R-loops: a potential advantage of having introns
<p>Abstract</p> <p>Background</p> <p>Accumulating evidence indicates that the nascent RNA can invade and pair with one strand of DNA, forming an R-loop structure that threatens the stability of the genome. In addition, the cost and benefit of introns are still in debate...
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| Format: | Article |
| Language: | English |
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BMC
2007-04-01
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| Series: | Biology Direct |
| Online Access: | http://www.biology-direct.com/content/2/1/11 |