Proteome Profiling of Cerebral Vessels in Rhesus Macaques: Dysregulation of Antioxidant Activity and Extracellular Matrix Proteins Contributes to Cerebrovascular Aging in Rhesus Macaques

Proteome Profiling of Cerebral Vessels in Rhesus Macaques: Dysregulation of Antioxidant Activity and Extracellular Matrix Proteins Contributes to Cerebrovascular Aging in Rhesus Macaques

Aging is a major risk factor for cerebrovascular disease; however, the molecular mechanisms of cerebrovascular aging remain to be clarified. The aim of this study was to reveal the molecular signaling pathways involved in cerebrovascular aging. This study used high-resolution liquid chromatography c...

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Bibliographic Details
Main Authors: Xia Wang, Yifan Liu, Yangjie Jia, Haotian Liu, Xinjie Bao, Zhanlong He, Wei Ge
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-10-01
Series:Frontiers in Aging Neuroscience
Subjects:
aging
rhesus macaque
cerebral vessels
proteomics
reactive oxygen species
extracellular matrix
Online Access:https://www.frontiersin.org/article/10.3389/fnagi.2019.00293/full

Internet

https://www.frontiersin.org/article/10.3389/fnagi.2019.00293/full

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