Inducing a Functional-Pharmacological Coupling in the Human Brain to Achieve Improved Drug Effect

Neuropharmacotherapy is substantially hindered by poor drug targeting, resulting in low specificity and efficacy. It is known that different behavioral tasks increase functional activity and cerebral blood flow (CBF), two key parameters controlling drug delivery and efficacy. Here, we tested a novel...

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Bibliographic Details
Main Authors: Roy Sar-El, Haggai Sharon, Nitzan Lubianiker, Talma Hendler, Gal Raz
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2020.557874/full