Zebrafish Mutants Carrying Leptin a (<em>lepa</em>) Gene Deficiency Display Obesity, Anxiety, Less Aggression and Fear, and Circadian Rhythm and Color Preference Dysregulation

Zebrafish Mutants Carrying Leptin a (<em>lepa</em>) Gene Deficiency Display Obesity, Anxiety, Less Aggression and Fear, and Circadian Rhythm and Color Preference Dysregulation

Leptin, a hormone secreted by peripheral adipose tissues, regulates the appetite in animals. Recently, evidence has shown that leptin also plays roles in behavioral response in addition to controlling appetite. In this study, we examined the potential function of leptin on non-appetite behaviors in...

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Bibliographic Details
Main Authors: Gilbert Audira, Sreeja Sarasamma, Jung-Ren Chen, Stevhen Juniardi, Bonifasius Putera Sampurna, Sung-Tzu Liang, Yu-Heng Lai, Geng-Ming Lin, Ming-Chia Hsieh, Chung-Der Hsiao
Format: Article
Language:English
Published: MDPI AG 2018-12-01
Series:International Journal of Molecular Sciences
Subjects:
leptin
obesity
zebrafish
behavior
anxiety
aggression
fear
circadian rhythm
color preference
genome editing
TALEN
Online Access:https://www.mdpi.com/1422-0067/19/12/4038

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https://www.mdpi.com/1422-0067/19/12/4038

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