Interplay between α2-chimaerin and Rac1 activity determines dynamic maintenance of long-term memory

Memory consolidation theory suggests that memory is maintained at a stable strength after formation. The authors show that memory is dynamically maintained at an intermediate level allowing a bidirectional regulation which is mediated by a balance between activated Rac1 and expressed α2-chimaerin.

Bibliographic Details
Main Authors: Li Lv, Yunlong Liu, Jianxin Xie, Yan Wu, Jianjian Zhao, Qian Li, Yi Zhong
Format: Article
Language:English
Published: Nature Publishing Group 2019-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-13236-9