Synthesis and in vitro biological evaluations of novel tetrapeptide as therapeutic agent for wound treatment

Synthesis and in vitro biological evaluations of novel tetrapeptide as therapeutic agent for wound treatment

We report a new small peptide containing four amino acid residues (glycine-aspartic acid-proline-histidine) conjugated with palmitic acid (Palmitoyl-GDPH) that was synthesized, characterized and evaluated for its biological activities. The Palmitoyl-GDPH was prepared by solid phase peptide synthesis...

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Bibliographic Details
Main Authors: Nur Izzah Md Fadilah, Haslina Ahmad, Mohd Basyaruddin Abdul Rahman, Suet Lin Chia, Shiow-Fern Ng, Sze Wei Leong
Format: Article
Language:English
Published: Elsevier 2020-08-01
Series:Journal of Saudi Chemical Society
Subjects:
Tetrapeptide
Therapeutic agent
Cytotoxicity
Cell proliferation
Cell migration
Wound healing
Online Access:http://www.sciencedirect.com/science/article/pii/S1319610320300788

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http://www.sciencedirect.com/science/article/pii/S1319610320300788

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