Cathelicidin Antimicrobial Peptides with Reduced Activation of Toll-Like Receptor Signaling Have Potent Bactericidal Activity against Colistin-Resistant Bacteria

The world is at the precipice of a postantibiotic era in which medical procedures and minor injuries can result in bacterial infections that are no longer effectively treated by antibiotics. Cathelicidins are peptides produced by animals to combat bacterial infections and to regulate innate immune r...

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Bibliographic Details
Main Authors: Cheng Kao, Xiaoyan Lin, Guanghui Yi, Yunliang Zhang, Dean A. Rowe-Magnus, Karen Bush
Format: Article
Language:English
Published: American Society for Microbiology 2016-09-01
Series:mBio
Online Access:http://mbio.asm.org/cgi/content/full/7/5/e01418-16