Study of the Relationships between the Structure, Lipophilicity and Biological Activity of Some Thiazolyl-carbonyl-thiosemicarbazides and Thiazolyl-azoles

Study of the Relationships between the Structure, Lipophilicity and Biological Activity of Some Thiazolyl-carbonyl-thiosemicarbazides and Thiazolyl-azoles

Lipophilicity, as one of the most important physicochemical parameters of bioactive molecules, was investigated for twenty-two thiazolyl-carbonyl-thiosemicarbazides and thiazolyl-azoles. The determination was carried out by reversed-phase thin-layer chromatography, using a binary isopropanol-water m...

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Bibliographic Details
Main Authors: Radu Tamaian, Augustin Moţ, Radu Silaghi-Dumitrescu, Ioana Ionuţ, Anca Stana, Ovidiu Oniga, Cristina Nastasă, Daniela Benedec, Brînduşa Tiperciuc
Format: Article
Language:English
Published: MDPI AG 2015-12-01
Series:Molecules
Subjects:
thiosemicarbazide
thiazolyl-azole
lipophilicity
PCA
anti-inflammatory
antioxidant
Online Access:http://www.mdpi.com/1420-3049/20/12/19841

Internet

http://www.mdpi.com/1420-3049/20/12/19841

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