BRD4 inhibition for the treatment of pathological organ fibrosis [version 1; referees: 2 approved]
Fibrosis is defined as excess deposition of extracellular matrix, resulting in tissue scarring and organ dysfunction. It is estimated that 45% of deaths in the developed world are due to fibrosis-induced organ failure. Despite the well-accepted role of fibrosis in the pathogenesis of numerous diseas...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
F1000 Research Ltd
2017-06-01
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Series: | F1000Research |
Subjects: | |
Online Access: | https://f1000research.com/articles/6-1015/v1 |