Violacein induces death of resistant leukaemia cells via kinome reprogramming, endoplasmic reticulum stress and Golgi apparatus collapse.

Violacein induces death of resistant leukaemia cells via kinome reprogramming, endoplasmic reticulum stress and Golgi apparatus collapse.

It is now generally recognised that different modes of programmed cell death (PCD) are intimately linked to the cancerous process. However, the mechanism of PCD involved in cancer chemoprevention is much less clear and may be different between types of chemopreventive agents and tumour cell types in...

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Main Authors: Karla C S Queiroz, Renato Milani, Roberta R Ruela-de-Sousa, Gwenny M Fuhler, Giselle Z Justo, Willian F Zambuzzi, Nelson Duran, Sander H Diks, C Arnold Spek, Carmen V Ferreira, Maikel P Peppelenbosch
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3469566?pdf=render

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http://europepmc.org/articles/PMC3469566?pdf=render

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