XBP-1 Remodels Lipid Metabolism to Extend Longevity
Summary: The endoplasmic reticulum unfolded protein response (UPRER) is a cellular stress response that maintains homeostasis within the secretory pathway, regulates glucose and lipid metabolism, and influences longevity. To ask whether this role in lifespan determination depends upon metabolic inte...
Main Authors: | Soudabeh Imanikia, Ming Sheng, Cecilia Castro, Julian L. Griffin, Rebecca C. Taylor |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2019-07-01
|
Series: | Cell Reports |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124719308307 |
Similar Items
-
XBP1s activation can globally remodel N-glycan structure distribution patterns
by: Wong, Madeline Y., et al.
Published: (2020) -
C. Elegans & anorectic herbal extracts : defining molecular-genetic responses & life-cycle consequences
by: Imanikia, Soudabeh
Published: (2015) -
The Role of Adipocyte XBP1 in Metabolic Regulation during Lactation
by: Margaret F. Gregor, et al.
Published: (2013-05-01) -
Vitamin D Promotes Protein Homeostasis and Longevity via the Stress Response Pathway Genes skn-1, ire-1, and xbp-1
by: Karla A. Mark, et al.
Published: (2016-10-01) -
Xbp1 directs global repression of budding yeast transcription during the transition to quiescence and is important for the longevity and reversibility of the quiescent state.
by: Shawna Miles, et al.
Published: (2013-10-01)