XBP-1 Remodels Lipid Metabolism to Extend Longevity

Summary: The endoplasmic reticulum unfolded protein response (UPRER) is a cellular stress response that maintains homeostasis within the secretory pathway, regulates glucose and lipid metabolism, and influences longevity. To ask whether this role in lifespan determination depends upon metabolic inte...

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Bibliographic Details
Main Authors: Soudabeh Imanikia, Ming Sheng, Cecilia Castro, Julian L. Griffin, Rebecca C. Taylor
Format: Article
Language:English
Published: Elsevier 2019-07-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124719308307