Mathematical identification of critical reactions in the interlocked feedback model.

Dynamic simulations are necessary for understanding the mechanism of how biochemical networks generate robust properties to environmental stresses or genetic changes. Sensitivity analysis allows the linking of robustness to network structure. However, it yields only local properties regarding a part...

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Bibliographic Details
Main Authors: Hiroyuki Kurata, Takayuki Tanaka, Fumitaka Ohnishi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2040204?pdf=render