Efficient synthesis of piperazinyl amides of 18β-glycyrrhetinic acid

In the present study, a practical method to prepare piperazinyl amides of 18β-glycyrrhetinic acid was developed. Two main procedures for the construction of important intermediate 8 are discussed. One procedure involves the amidation of 1-Boc-piperazine with 3-acetyl-18β-glycyrrhetinic acid, prepare...

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Bibliographic Details
Main Authors: Dong Cai, ZhiHua Zhang, Yufan Meng, KaiLi Zhu, LiYi Chen, ChangXiang Yu, ChangWei Yu, ZiYi Fu, DianShen Yang, YiXia Gong
Format: Article
Language:English
Published: Beilstein-Institut 2020-04-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
Online Access:https://doi.org/10.3762/bjoc.16.73