Reduced intensity of early intensification does not increase the risk of relapse in children with standard risk acute lymphoblastic leukemia - a multi-centric clinical study of GD-2008-ALL protocol

Reduced intensity of early intensification does not increase the risk of relapse in children with standard risk acute lymphoblastic leukemia - a multi-centric clinical study of GD-2008-ALL protocol

Abstract Background The prognosis of childhood acute lymphoblastic leukemia (ALL) is optimistic with a 5-year event-free survival (EFS) rate of 70–85%. However, the major causes of mortality are chemotherapy toxicity, infection and relapse. The Guangdong (GD)-2008-ALL collaborative protocol was carr...

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Bibliographic Details
Main Authors: Xin-Yu Li, Jia-Qiang Li, Xue-Qun Luo, Xue-Dong Wu, Xin Sun, Hong-Gui Xu, Chang-Gang Li, Ri-Yang Liu, Xiao-Fei Sun, Hui-Qin Chen, Yu-Deng Lin, Chi-kong LI, Jian-Pei Fang
Format: Article
Language:English
Published: BMC 2021-01-01
Series:BMC Cancer
Subjects:
Acute lymphoblastic leukemia
Children
Chemotherapy
Reduced intensity multi-centric clinical study
Online Access:https://doi.org/10.1186/s12885-020-07752-x

Internet

https://doi.org/10.1186/s12885-020-07752-x

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