Comparative pharmacokinetics of six major compounds in normal and insomnia rats after oral administration of Ziziphi Spinosae Semen aqueous extract

Ziziphi Spinosae Semen (ZSS), a traditional Chinese medicine, is used in clinics for the treatment of insomnia in China and other Asian countries. Herein, we described for the first time a comparative pharmacokinetics study of the six major compounds of ZSS in normal control (NC) and para-chlorophen...

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Bibliographic Details
Main Authors: Chenhui Du, Yan Yan, Chenxi Shen, Xiaofang Cui, Xiangping Pei, Xuemei Qin
Format: Article
Language:English
Published: Elsevier 2020-08-01
Series:Journal of Pharmaceutical Analysis
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2095177919308512