Role of Beclin-1-Mediated Autophagy in the Survival of Pediatric Leukemia Cells

Role of Beclin-1-Mediated Autophagy in the Survival of Pediatric Leukemia Cells

Background/Aims: Acute and chronic leukemia are severe malignant cancers worldwide, and can occur in pediatric patients. Since bone marrow cell transplantation is seriously limited by the availability of the immune-paired donor sources, the therapy for pediatric leukemia (PL) remains challenging. Au...

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Bibliographic Details
Main Authors: Xiaoli Wu, Xuefeng Feng, Xiaoqing Zhao, Futian Ma, Na Liu, Hongming Guo, Chaonan Li, Huan Du, Baoxi Zhang
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2016-10-01
Series:Cellular Physiology and Biochemistry
Subjects:
Pediatric leukemia (PL)
Oxidative stress
Autophagy
Apoptosis
Beclin-1
miR-93
Online Access:http://www.karger.com/Article/FullText/447882

Internet

http://www.karger.com/Article/FullText/447882

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