miR-125b acts as a tumor suppressor in breast tumorigenesis via its novel direct targets ENPEP, CK2-α, CCNJ, and MEGF9.

MicroRNAs (miRNAs) play important roles in diverse biological processes and are emerging as key regulators of tumorigenesis and tumor progression. To explore the dysregulation of miRNAs in breast cancer, a genome-wide expression profiling of 939 miRNAs was performed in 50 breast cancer patients. A t...

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Main Authors: Andrea Feliciano, Josep Castellvi, Ana Artero-Castro, Jose A Leal, Cleofé Romagosa, Javier Hernández-Losa, Vicente Peg, Angels Fabra, Francisco Vidal, Hiroshi Kondoh, Santiago Ramón Y Cajal, Matilde E Lleonart
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24098452/?tool=EBI