Experimental assessment of static and dynamic algorithms for gene regulation inference from time series expression data

Accurate inference of causal gene regulatory networks from gene expression data is an open bioinformatics challenge. Gene interactions are dynamical processes and consequently we can expect that the effect of any regulation action occurs after a certain temporal lag. However such lag is unknown a pr...

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Bibliographic Details
Main Authors: Miguel eLopes, Gianluca eBontempi
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-12-01
Series:Frontiers in Genetics
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2013.00303/full