Anti-fibrotic effects of L-2-oxothiazolidine-4-carboxylic acid via modulation of nuclear factor erythroid 2-related factor 2 in rats

Anti-fibrotic effects of L-2-oxothiazolidine-4-carboxylic acid via modulation of nuclear factor erythroid 2-related factor 2 in rats

L-2-Oxothiazolidine-4-carboxylic acid (OTC) is a cysteine prodrugthat maintains glutathione in tissues. The present studywas designed to investigate anti-fibrotic and anti-oxidative effectsof OTC via modulation of nuclear factor erythroid 2-relatedfactor 2 (Nrf2) in an in vivo thioacetamide (TAA)-in...

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Bibliographic Details
Main Author: In Hee Kim1,2, Dae-Ghon Kim1,2*, Peipei Hao2, Yunpeng Wang2, Seong Hun Kim1,2, Sang Wook Kim1,2, Seung Ok Lee1,2 & Soo Teik Lee1,2
Format: Article
Language:English
Published: Korean Society for Biochemistry and Molecular Biology 2012-06-01
Series:BMB Reports
Subjects:
L-2-Oxothiazolidine-4-carboxylic acid
Liver fibrosis
Nrf2
Oxidative stress
Thioacetamide
Online Access:http://www.jbmb.or.kr/jbmb/pdf.php?data=MTMwMTIyMTdAcGRmX3JhaW50cmFjZV9sZWV5c0AlNUI0NS02JTVEMTIwNjI2MDcxM18lMjgzNDgtMzUzJTI5Qk1CXzExLTI3Ni5wZGY=

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http://www.jbmb.or.kr/jbmb/pdf.php?data=MTMwMTIyMTdAcGRmX3JhaW50cmFjZV9sZWV5c0AlNUI0NS02JTVEMTIwNjI2MDcxM18lMjgzNDgtMzUzJTI5Qk1CXzExLTI3Ni5wZGY=

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