Rapid Modulation of Axon Initial Segment Length Influences Repetitive Spike Firing

Neurons implement a variety of plasticity mechanisms to alter their function over timescales ranging from seconds to days. One powerful means of controlling excitability is to directly modulate the site of spike initiation, the axon initial segment (AIS). However, all plastic structural AIS changes...

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Bibliographic Details
Main Authors: Mark D. Evans, Adna S. Dumitrescu, Dennis L.H. Kruijssen, Samuel E. Taylor, Matthew S. Grubb
Format: Article
Language:English
Published: Elsevier 2015-11-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124715011080