Effect of Hypromellose Acetate Succinate Substituents on Miscibility Behavior of Spray-dried Amorphous Solid Dispersions: Flory–Huggins Parameter Prediction and Validation
ABSTRACT: This study reports the impact of physicochemical properties of lipophilic drugs such as Fenofibrate (FBT), Itraconazole (ITZ), Efavirenz (EFV) and Hydroxypropyl Methylcellulose Acetate Succinate (HPMCAS) grades on the miscibility, dissolution, and stability of the spray dried Amorphous Sol...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2021-12-01
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| Series: | Carbohydrate Polymer Technologies and Applications |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2666893921001055 |