Randomised controlled trial of Tumour necrosis factor inhibitors Against Combination Intensive Therapy with conventional disease-modifying antirheumatic drugs in established rheumatoid arthritis: the TACIT trial and associated systematic reviews

Background: Rheumatoid arthritis (RA) is initially treated with methotrexate and other disease-modifying antirheumatic drugs (DMARDs). Active RA patients who fail such treatments can receive tumour necrosis factor inhibitors (TNFis), which are effective but expensive. Objective: We assessed whether...

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Bibliographic Details
Main Authors: David L Scott, Fowzia Ibrahim, Vern Farewell, Aidan G O’Keeffe, Margaret Ma, David Walker, Margaret Heslin, Anita Patel, Gabrielle Kingsley
Format: Article
Language:English
Published: NIHR Journals Library 2014-10-01
Series:Health Technology Assessment
Online Access:https://doi.org/10.3310/hta18660