Cryopreservation of Human Pancreatic Islets from Non-Heart-Beating Donors Using Hydroxyethyl Starch and Dimethyl Sulfoxide as Cryoprotectants
Although widely used, DMSO is toxic for pancreatic islets. We combined hydroxyethyl starch (HES) with DMSO to simplify the procedure of freezing and thawing, and to decrease the toxicity of DMSO. A preclinical study was performed using islets from beagle dogs. After storage for 4 weeks, the islets w...
| Main Authors: | , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2008-01-01
|
| Series: | Cell Transplantation |
| Online Access: | https://doi.org/10.3727/000000008783907026 |