DNA Methylation variability among individuals is related to CpGs cluster density and evolutionary signatures

Abstract Background In recent years, epigenetics has gained a central role in the understanding of the process of natural selection. It is now clear how environmental impacts on the methylome could promote methylation variability with direct effects on disease etiology as well as phenotypic and geno...

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Bibliographic Details
Main Authors: Domenico Palumbo, Ornella Affinito, Antonella Monticelli, Sergio Cocozza
Format: Article
Language:English
Published: BMC 2018-04-01
Series:BMC Genomics
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12864-018-4618-9