Chitosan-Coated Hydroxypropylmethyl Cellulose Microparticles of Levodopa (and Carbidopa): In Vitro and Rat Model Kinetic Characteristics

Chitosan-Coated Hydroxypropylmethyl Cellulose Microparticles of Levodopa (and Carbidopa): In Vitro and Rat Model Kinetic Characteristics

ABSTRACT: Background: Parkinson's disease is a neurodegenerative disorder, and a major cause of disability. Levodopa, a prodrug of dopamine, remains the gold standard in the pharmacological management of Parkinson's disease. Despite several attempts to improve the clinical efficacy of lev...

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Bibliographic Details
Main Authors: Benedicta Obenewaa Dankyi, MPhil, Seth Kwabena Amponsah, PhD, Grace Lovia Allotey-Babington, PhD, Ismaila Adams, BPharm, Nana Aboadwe Goode, BPharm, Henry Nettey, PharmD/PhD
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Current Therapeutic Research
Subjects:
levodopa
microparticles
Parkinson's disease
pharmacokinetics
Online Access:http://www.sciencedirect.com/science/article/pii/S0011393X20300382

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http://www.sciencedirect.com/science/article/pii/S0011393X20300382

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