A mechanistic investigation exploring the differential transfection efficiencies between the easy-to-transfect SK-BR3 and difficult-to-transfect CT26 cell lines

Abstract Background Gold–polyamidoamine (AuPAMAM) has previously been shown to successfully transfect cells with high efficiency. However, we have observed that certain cell types are more amenable to Au–PAMAM transfection than others. Here we utilized two representative cell lines—a “difficult to t...

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Bibliographic Details
Main Authors: Elizabeth Figueroa, Pallavi Bugga, Vishwaratn Asthana, Allen L. Chen, J. Stephen Yan, Emily Reiser Evans, Rebekah A. Drezek
Format: Article
Language:English
Published: BMC 2017-05-01
Series:Journal of Nanobiotechnology
Subjects:
PEI
Online Access:http://link.springer.com/article/10.1186/s12951-017-0271-8