Integrative genomic study of Chinese clear cell renal cell carcinoma reveals features associated with thrombus
The genomic heterogeneity of clear cell renal cell carcinoma (ccRCC) across populations is poorly understood. Here, the authors analyse a cohort of Chinese ccRCC cases revealing a mutational signature associated with aristolochic acid exposure, and higher mutational burden and enrichment for BAP1 an...
Main Authors: | , , , , , , , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2020-02-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-020-14601-9 |