Pan-Cancer Analysis and Drug Formulation for GPR139 and GPR142

Pan-Cancer Analysis and Drug Formulation for GPR139 and GPR142

GPR (G protein receptor) 139 and 142 are novel foundling GPCRs (G protein-coupled receptors) in the class “A” of the GPCRs family and are suitable targets for various biological conditions. To engage these targets, validated pharmacophores and 3D QSAR (Quantitative structure-activity relationship) m...

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Bibliographic Details
Main Authors: Aman Chandra Kaushik, Aamir Mehmood, Xiaofeng Dai, Dong-Qing Wei
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Pharmacology
Subjects:
GPR142
molecular modeling
pharmacophore
3D quantitative structure-activity relationship
7TM
pan-cancer
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2020.521245/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2020.521245/full

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