A knowledge-based method for association studies on complex diseases.

Complex disorders are a class of diseases whose phenotypic variance is caused by the interplay of multiple genetic and environmental factors. Analyzing the complexity underlying the genetic architecture of such traits may help develop more efficient diagnostic tests and therapeutic protocols. Despit...

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Bibliographic Details
Main Authors: Alireza Nazarian, Heike Sichtig, Alberto Riva
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3435396?pdf=render