High shear stress enhances endothelial permeability in the presence of the risk haplotype at 9p21.3

Single nucleotide polymorphisms (SNPs) are exceedingly common in non-coding loci, and while they are significantly associated with a myriad of diseases, their specific impact on cellular dysfunction remains unclear. Here, we show that when exposed to external stressors, the presence of risk SNPs in...

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Bibliographic Details
Main Authors: Evan L. Teng, Evan M. Masutani, Benjamin Yeoman, Jessica Fung, Rachel Lian, Brenda Ngo, Aditya Kumar, Jesse K. Placone, Valentina Lo Sardo, Adam J. Engler
Format: Article
Language:English
Published: AIP Publishing LLC 2021-09-01
Series:APL Bioengineering
Online Access:http://dx.doi.org/10.1063/5.0054639