In Vitro Evaluation of the Squaramide-Conjugated Fibroblast Activation Protein Inhibitor-Based Agents AAZTA<sup>5</sup>.SA.FAPi and DOTA.SA.FAPi

In Vitro Evaluation of the Squaramide-Conjugated Fibroblast Activation Protein Inhibitor-Based Agents AAZTA<sup>5</sup>.SA.FAPi and DOTA.SA.FAPi

Recently, the first squaramide-(SA) containing FAP inhibitor-derived radiotracers were introduced. DATA<sup>5m</sup>.SA.FAPi and DOTA.SA.FAPi with their non-radioactive complexes showed high affinity and selectivity for FAP. After a successful preclinical study with [<sup>68</su...

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Bibliographic Details
Main Authors: Euy Sung Moon, Yentl Van Rymenant, Sandeep Battan, Joni De Loose, An Bracke, Pieter Van der Veken, Ingrid De Meester, Frank Rösch
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Molecules
Subjects:
AAZTA
scandium-44
lutetium-177
FAP
SA
DPP
Online Access:https://www.mdpi.com/1420-3049/26/12/3482

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