Notch1 regulated autophagy controls survival and suppressor activity of activated murine T-regulatory cells

Cell survival is one of several processes regulated by the Notch pathway in mammalian cells. Here we report functional outcomes of non-nuclear Notch signaling to activate autophagy, a conserved cellular response to nutrient stress, regulating survival in murine natural T-regulatory cells (Tregs), an...

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Bibliographic Details
Main Authors: Nimi Marcel, Apurva Sarin
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2016-06-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/14023