Transgenic mouse model for estrogen-regulated lipoprotein metabolism: studies on apoVLDL-II expression in transgenic mice
We have produced transgenic mice that express an estrogen-responsive avian apolipoprotein, apoVLDL-II. An apoVLDL-II natural gene construct containing 4.7 kb of 5‘ flanking and 19 bp of 3‘ flanking sequences together with the 4 exon/3 intron structural gene was expressed in a liver-specific manner i...
Main Authors: | E Zsigmond, M K Nakanishi, F E Ghiselli, L Chan |
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Format: | Article |
Language: | English |
Published: |
Elsevier
1995-07-01
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Series: | Journal of Lipid Research |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0022227520397327 |
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