Transgenic mouse model for estrogen-regulated lipoprotein metabolism: studies on apoVLDL-II expression in transgenic mice

We have produced transgenic mice that express an estrogen-responsive avian apolipoprotein, apoVLDL-II. An apoVLDL-II natural gene construct containing 4.7 kb of 5‘ flanking and 19 bp of 3‘ flanking sequences together with the 4 exon/3 intron structural gene was expressed in a liver-specific manner i...

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Bibliographic Details
Main Authors: E Zsigmond, M K Nakanishi, F E Ghiselli, L Chan
Format: Article
Language:English
Published: Elsevier 1995-07-01
Series:Journal of Lipid Research
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520397327