Possible Mechanisms by which Stefin B could Regulate Proteostasis and Oxidative Stress
Human stefin B is a protease inhibitor from the family of cystatins. It was reported that it forms oligomers in cells. We have shown that it has a role in cell’s response to misfolded proteins. We also have shown that its oligomers bind amyloid-beta (Aβ). Here, we discuss ways, ho...
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Format: | Article |
Language: | English |
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MDPI AG
2019-01-01
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Series: | Cells |
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Online Access: | http://www.mdpi.com/2073-4409/8/1/70 |