Identification of miR-200a-5p targeting the peptide transporter TAP1 and its association with the clinical outcome of melanoma patients

Identification of miR-200a-5p targeting the peptide transporter TAP1 and its association with the clinical outcome of melanoma patients

Tumor escape is often associated with abnormalities in the surface expression of the human leukocyte antigen class I (HLA-I) antigens thereby limiting CD8+ cytotoxic T cell responses. This impaired HLA-I surface expression can be mediated by deficient expression of components of the antigen processi...

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Bibliographic Details
Main Authors: Maria-Filothei Lazaridou, Evamaria Gonschorek, Chiara Massa, Michael Friedrich, Diana Handke, Anja Mueller, Simon Jasinski-Bergner, Reinhard Dummer, Peter Koelblinger, Barbara Seliger
Format: Article
Language:English
Published: Taylor & Francis Group 2020-01-01
Series:OncoImmunology
Subjects:
peptide transporter
hla
tumor
microrna
immune escape
Online Access:http://dx.doi.org/10.1080/2162402X.2020.1774323

Internet

http://dx.doi.org/10.1080/2162402X.2020.1774323

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