Epithelial-mesenchymal transition associates with maintenance of stemness in spheroid-derived stem-like colon cancer cells.

Despite earlier studies demonstrating characteristics of colon cancer stem cells (CCSCs) and the role of epithelial-mesenchymal transition (EMT) in tumor development, it remains controversial as to the relationship between CCSCs and EMT. In this study, in order to present an insight into this relati...

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Bibliographic Details
Main Authors: Xiao-Yan Han, Bo Wei, Jia-Feng Fang, Shi Zhang, Fu-Cheng Zhang, Hai-Bo Zhang, Tian-Yun Lan, Hui-Qiong Lu, Hong-Bo Wei
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3767831?pdf=render