Structural Analysis of the Hanks-Type Protein Kinase YabT From Bacillus subtilis Provides New Insights in its DNA-Dependent Activation

Structural Analysis of the Hanks-Type Protein Kinase YabT From Bacillus subtilis Provides New Insights in its DNA-Dependent Activation

YabT is a serine/threonine kinase of the Hanks family from Bacillus subtilis, which lacks the canonical extracellular signal receptor domain but is anchored to the membrane through a C-terminal transmembrane helix. A previous study demonstrated that a basic juxtamembrane region corresponds to a DNA-...

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Bibliographic Details
Main Authors: Lei Shi, Andrea Cavagnino, Jean-Luc Rabefiraisana, Noureddine Lazar, Inès Li de la Sierra-Gallay, Françoise Ochsenbein, Marie Valerio-Lepiniec, Agathe Urvoas, Philippe Minard, Ivan Mijakovic, Sylvie Nessler
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-01-01
Series:Frontiers in Microbiology
Subjects:
autophosphorylation
dimerization
regulatory mechanism
crystallization chaperone
spore development
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2018.03014/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2018.03014/full

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