Modeling ex vivo tumor-infiltrating lymphocyte expansion from established solid malignancies

Modeling ex vivo tumor-infiltrating lymphocyte expansion from established solid malignancies

Adoptive transfer of tumor-infiltrating lymphocytes (TIL) elicits the regression of metastatic malignancies, yet a low proportion of patients achieve complete durable responses. The high incidence of relapse in these patients highlights the need to better understand mechanisms of tumor escape from T...

Full description

Bibliographic Details
Main Authors: Hannah M Knochelmann, Amalia M Rivera-Reyes, Megan M Wyatt, Aubrey S Smith, Reilley Chamness, Connor J Dwyer, Michael Bobian, Guillermo O Rangel Rivera, Joshua D Horton, Michael Lilly, Martin J Romeo, Cynthia D Timmers, Mark P Rubinstein, David M Neskey, Chrystal M Paulos
Format: Article
Language:English
Published: Taylor & Francis Group 2021-01-01
Series:OncoImmunology
Subjects:
adoptive t cell therapy
til therapy
tumor-infiltrating lymphocyte
solid tumors
t cell
act
Online Access:http://dx.doi.org/10.1080/2162402X.2021.1959101

Internet

http://dx.doi.org/10.1080/2162402X.2021.1959101

Similar Items