Measles Virus Infection Fosters Dendritic Cell Motility in a 3D Environment to Enhance Transmission to Target Cells in the Respiratory Epithelium

Measles Virus Infection Fosters Dendritic Cell Motility in a 3D Environment to Enhance Transmission to Target Cells in the Respiratory Epithelium

Transmission of measles virus (MV) from dendritic to airway epithelial cells is considered as crucial to viral spread late in infection. Therefore, pathways and effectors governing this process are promising targets for intervention. To identify these, we established a 3D respiratory tract model whe...

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Bibliographic Details
Main Authors: Shaghayegh Derakhshani, Andreas Kurz, Lukasz Japtok, Fabian Schumacher, Lisa Pilgram, Maria Steinke, Burkhard Kleuser, Markus Sauer, Sibylle Schneider-Schaulies, Elita Avota
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-06-01
Series:Frontiers in Immunology
Subjects:
dendritic cell
cell migration
measles virus
3D tissue model
sphingosine-1-phosphate
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.01294/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.01294/full

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