Baculovirus-free insect cell expression system for high yield antibody and antigen production

Baculovirus-free insect cell expression system for high yield antibody and antigen production

Abstract Antibodies are essential tools for therapy and diagnostics. Yet, production remains expensive as it is mostly done in mammalian expression systems. As most therapeutic IgG require mammalian glycosylation to interact with the human immune system, other expression systems are rarely used for...

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Bibliographic Details
Main Authors: Janin Korn, Dorina Schäckermann, Toni Kirmann, Federico Bertoglio, Stephan Steinke, Janyn Heisig, Maximilian Ruschig, Gertrudis Rojas, Nora Langreder, Esther Veronika Wenzel, Kristian Daniel Ralph Roth, Marlies Becker, Doris Meier, Joop van den Heuvel, Michael Hust, Stefan Dübel, Maren Schubert
Format: Article
Language:English
Published: Nature Publishing Group 2020-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-78425-9

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https://doi.org/10.1038/s41598-020-78425-9

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