Long-Term Labeling of Hippocampal Neural Stem Cells by a Lentiviral Vector

Long-Term Labeling of Hippocampal Neural Stem Cells by a Lentiviral Vector

Using a lentivirus-mediated labeling method, we investigated whether the adult hippocampus retains long-lasting, self-renewing neural stem cells (NSCs). We first showed that a single injection of a lentiviral vector expressing a green fluorescent protein (LV PGK-GFP) into the subgranular zone (SGZ)...

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Bibliographic Details
Main Authors: Hoonkyo Suh, Qi-Gang Zhou, Irene Fernandez-Carasa, Gregory Dane Clemenson, Meritxell Pons-Espinal, Eun Jeoung Ro, Mercè Marti, Angel Raya, Fred H. Gage, Antonella Consiglio
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Molecular Neuroscience
Subjects:
lentiviral vectors
hippocampal neurogenesis
targeting
neural stem cells
lesion
Online Access:https://www.frontiersin.org/article/10.3389/fnmol.2018.00415/full

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https://www.frontiersin.org/article/10.3389/fnmol.2018.00415/full

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