Effect of memantine on the survival of an ischemic random skin flap and the underlying mechanism

Background: Skin flap transplantation is a common wound repair method in orthopedic surgery, but skin flap necrosis remains problematic. Memantine, an excitatory amino acid receptor antagonist, is currently used in the treatment of moderate to severe Alzheimer's disease, due to its ability to p...

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Bibliographic Details
Main Authors: Weijian Fan, Zhenhua Liu, Jianpeng Chen, Shaodong Liu, Tingxiang Chen, Zhijie Li, Dingsheng Lin
Format: Article
Language:English
Published: Elsevier 2021-11-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332221009471