Global loss of bmal1 expression alters adipose tissue hormones, gene expression and glucose metabolism.

The close relationship between circadian rhythm disruption and poor metabolic status is becoming increasingly evident, but role of adipokines is poorly understood. Here we investigated adipocyte function and the metabolic status of mice with a global loss of the core clock gene Bmal1 fed either a no...

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Bibliographic Details
Main Authors: David John Kennaway, Tamara Jayne Varcoe, Athena Voultsios, Michael James Boden
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3672145?pdf=render