A Broad-Spectrum Antiviral Peptide Blocks Infection of Viruses by Binding to Phosphatidylserine in the Viral Envelope

A Broad-Spectrum Antiviral Peptide Blocks Infection of Viruses by Binding to Phosphatidylserine in the Viral Envelope

The ongoing threat of viral infections and the emergence of antiviral drug resistance warrants a ceaseless search for new antiviral compounds. Broadly-inhibiting compounds that act on elements shared by many viruses are promising antiviral candidates. Here, we identify a peptide derived from the cow...

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Bibliographic Details
Main Authors: Rutger D. Luteijn, Patrique Praest, Frank Thiele, Saravanan Manikam Sadasivam, Katrin Singethan, Jan W. Drijfhout, Christian Bach, Steffen Matthijn de Boer, Robert J. Lebbink, Sha Tao, Markus Helfer, Nina C. Bach, Ulrike Protzer, Ana I. Costa, J. Antoinette Killian, Ingo Drexler, Emmanuel J. H. J. Wiertz
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Cells
Subjects:
antiviral peptide
enveloped viruses
membrane phosphatidylserine
envelope disruption
Online Access:https://www.mdpi.com/2073-4409/9/9/1989

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https://www.mdpi.com/2073-4409/9/9/1989

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